Does seroquel weaken your immune system?

Low White Blood Cell Count: Seroquel may reduce the number of white blood cells (WBC) in the body, especially among those with a history of low WBCs.

Can seroquel cause vasculitis?

So far, there is one report of vasculitis associated with quetiapine use. [1] Here, we present a case of quetiapine-induced LCV, which is an unusual side effect of quetiapine.

What causes Linear IgA dermatosis?

The underlying cause of linear IgA bullous dermatosis (LABD) is circulating IgA anti-basement membrane zone antibodies directed against the 97 kDa portion of BPAG2 (bullous pemphigoid antigen 2, also known as BP180) in the lamina lucida. The 97 kDa subunit lies within the well-known NC16A domain of the BPAG2 molecule.

How do you get linear IgA disease?

The exact cause of Linear IgA Disease is unknown however it is considered to be an “autoimmune” disease. The body’s immune system produces antibodies known as Immunoglobulin A (IgA) which are incorrectly deposited in the top layer of the skin in a line – hence the term “linear”.

What is the difference between Seroquel XR and regular Seroquel?

Seroquel is available as tablets (25, 100, 150, 200 and 300 mg) while Seroquel XR is available as prolonged-release tablets (50, 150, 200, 300 and 400 mg). Prolonged-release means that the active substance is released slowly from the tablet over a few hours.

Does Seroquel make you itchy?

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

What drug class is quetiapine?

Quetiapine is in a class of medications called atypical antipsychotics. It works by changing the activity of certain natural substances in the brain.

How long does linear IgA last?

The mean duration of idiopathic linear IgA dermatosis of childhood is 3.9 years, ranging from 2.1-7.9 years. Remission has been reported to occur in 64% of children, in most cases within 2 years. Disease of adults is more protracted, with a mean duration of 5.6 years, lasting anywhere from 1-15 years.

How common is linear IgA disease?

Linear immunoglobulin A (IgA) bullous dermatosis, also known as linear IgA disease, is a rare disorder with an incidence of about 0.5 to 2.3 cases per million individuals per year. In most of the cases, the cause is unknown; however, 50% of the cases are drug-induced.

Is linear IgA an autoimmune disease?

Linear immunoglobulin A (IgA) dermatosis (LAD) is an autoimmune subepidermal vesiculobullous disease that may be idiopathic or drug-induced. Children and adults are affected, with disease of the former historically referred to as chronic bullous dermatosis of childhood.

Is Seroquel safe long-term?

High doses or long-term use of quetiapine can cause a serious movement disorder that may not be reversible. The longer you use quetiapine, the more likely you are to develop this disorder, especially if you are an older adult. Symptoms of this disorder include tremors or other uncontrollable muscle movements.

What is Seroquel® (quetiapine fumarate)?

SEROQUEL® (quetiapine fumarate) is a psychotropic agent belonging to a chemical class, the dibenzothiazepine derivatives. The chemical designation is 2-[2-(4-dibenzo [b,f]…

How many immunoglobulins are in Iga?

Detection or monitoring of IgA monoclonal gammopathies and IgA-related immune deficiencies The gamma globulin band as seen in conventional serum protein electrophoresis consists of 5 immunoglobulins. In normal serum, about 15% is immunoglobulin A (IgA).

What causes IgA in the glomeruli?

The IgA protein is a normal part of the body’s immune system. It is not known what causes IgA deposits in the glomeruli. In more than 10% of affected families, it is inherited. Some people who inherit the gene may not have any symptoms, but could pass the gene on. Men are affected more often than women.

What is the IgA protease for nephropathy?

On Dec 3rd of 2007 BioMarin Pharmaceuticals and IGAN Biosciences announced a collaboration to initiate a program to develop an IgA protease for treating IgA Nephropathy. IgA protease is shown to cleave the IgA complex which can casue the nephropathy.