How do you reduce Nitro in amine?
How do you reduce Nitro in amine?
Aliphatic nitro compounds can be reduced to aliphatic amines by several reagents:
- Catalytic hydrogenation using platinum(IV) oxide (PtO2) or Raney nickel.
- Iron metal in refluxing acetic acid.
- Samarium diiodide.
- Raney nickel, platinum on carbon, or zinc dust and formic acid or ammonium formate.
How do you convert a nitro group to amines?
One of the most important reactions of aromatic substituents is the reduction of nitro groups to amines. This can be done using two general methods: Addition of an easily oxidized metal like iron (Fe), tin (Sn) or zinc (Zn) in the presence of acid, such as HCl (but often just written, “H+ “) will convert NO2 to NH2.
Can LiAlH4 reduce NO2 to NH2?
The answer is No. LAH is a nucleophilic reductant providing H- ions that reacts with electrophiles.
How do you selectively reduce nitro group?
Sodium sulfide can be used to reduce selectively aromatic / aliphatic nitro groups. In the absence of water, the aromatic nitro group can be reduced selectively in the presence of a secondary aliphatic one.
Which reducing agent is used for the reduction of nitro compound of phenyl amine?
4. Which reducing agent is used for the reduction of nitro compound to phenyl amine? Explanation: Aromatic amines were prepared in good yields by a novel reduction of aromatic nitro compounds with tin metal in hydrochloric acid. 5.
Which reducing agent is used for the reduction of nitro compound to phenyl amine?
Explanation: Nitrobenzene is reduced to phenyl ammonium(A) ions using a mixture of tin and concentrated hydrochloric acid. The phenylamine(B) is formed together with a complicated mixture of tin compounds from reactions between the sodium hydroxide solution and the complex tin ions formed.
Can LiAlH4 reduce Nitro to Amine?
Lithium aluminum hydride (LiAlH4) reduces aliphatic nitro compounds to amines, but aromatic nitro compounds produce azo products. LiAlH4 is a common reagent for the reduction of nitroalkenes that have been formed using Henry reactions.
Can LiAlH4 reduce cinnamic acid?
LiAlH4 reduces double bond in case of only when it is conjugation with phenyl ring but “cinnamic acid” is an excepection because it has both carbonyl carbon as well as phenyl ring in its conjugation.