What is Antimog disease?

Anti-MOG syndrome is an autoimmune disorder in which the immune system mistakenly attacks myelin oligodendrocyte glycoprotein (MOG). This protein is located on the surface of myelin, an insulating layer that protects nerve cells and helps facilitate communication between them.

What is myelin oligodendrocyte glycoprotein MOG antibody disorder?

Myelin oligodendrocyte glycoprotein (MOG)-associated disease (MOGAD) is a rare, antibody-mediated inflammatory demyelinating disorder of the central nervous system (CNS) with various phenotypes starting from optic neuritis, via transverse myelitis to acute demyelinating encephalomyelitis (ADEM) and cortical …

Is MOG an autoimmune disease?

Like NMO, MOG antibody disease is an autoimmune disease of the central nervous system (CNS).

What is the life expectancy of someone with MOG?

NMO is also known as Devic’s disease or neuromyelitis optica spectrum disorder (NMOSD). Patients with neuromyelitis optica (NMO) patients have a 91% to 98% five-year survival rate. Current research indicates that neuromyelitis optica (NMO) patients have a 91% to 98% five-year survival rate.

What are the symptoms of ADEM?

Acute Disseminated Encephalomyelitis (ADEM) | Symptoms & Causes

• nausea and vomiting.
• headache.
• confusion.
• weakness.
• ataxia (unsteady walk)
• sensory changes, including numbness or tingling.
• optic neuritis (trouble with vision)
• seizures.

Is Mogad curable?

Although it can be treated, it is very devastating and sometimes fatal. It is important to know that exposure to these medications in MOG antibody disease has not led to a known case of PML.

Is MOG disease fatal?

What is the difference between MOG and MS?

MOGAD patients are slightly younger and have less of a female predominance than MS. Although MOG patients often will have abnormalities on brain MRI these lesions have a distinct appearance that is different from MS lesions.

Is ADEM life threatening?

Severe cases of ADEM can be fatal but this is a very rare occurrence. ADEM can recur, usually within months of the initial diagnosis, and is treated by restarting corticosteroids.

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