What is methyl 2 pyrrolidinone used for?

N-Methylpyrrolidone (NMP) is a solvent used in a variety of industries and applications, such as paint and coating removal, petrochemical processing, engineering plastics coatings, agricultural chemicals, electronic cleaning and industrial/domestic cleaning.

How is NMP made?

NMP is produced industrially by a typical ester-to-amide conversion, by treating butyrolactone with methylamine. Alternative routes include the partial hydrogenation of N-methylsuccinimide and the reaction of acrylonitrile with methylamine followed by hydrolysis. About 20,000 to 30,000 tons are produced annually.

Is NMP toxic?

The European Chemicals Agency classifies NMP as a “Substance of Very High Concern” because of its toxicity to reproduction based on developmental toxicity.

Is NMP carcinogenic?

EPA and other regulatory bodies have not classified NMP as to its carcinogenicity in humans.

How do I remove NMP solvent?

Centrifugal evaporators that can remove NMP are available, however they are expensive and no system, can remove 100% of any solvent. Removing NMP under vacuum requires a good, oil free vacuum pump of the scroll style, a diaphragm pump is not strong enough, a cold trap with sub zero cabability, and a heated system.

Is NMP flammable?

Hazard Class: 3 (Flammable) 1-Methyl-2-Pyrrolidone is a COMBUSTIBLE LIQUID. Use dry chemical, CO2, water spray or alcohol-resistant foam as extinguishing agents. POISONOUS GASES ARE PRODUCED IN FIRE, including Nitrogen Oxides. Use water spray to keep fire-exposed containers cool.

How do you make methyl 2 pyrrolidone?

N-Methyl-2-pyrrolidone (NMP) is prepared by preparing a mixture comprising monomethylamine, dimethylamine and trimethylamine and ammonia in a first process step by reacting ammonia with methanol at elevated temperature in the presence of a catalyst, separating 10 off the ammonia, reacting the mixture comprising the …

Where is NMP found?

NMP, one of the first 10 chemicals, is commonly used in paint and coating removal products but is also found in automotive products, inks, degreasers, and more. NMP is linked to fetal development problems, including low birth weight and birth defects.

Where can I store my NMP?

NMP samples are safely stored in clear glass bottles or steel cans with sufficient vapor space to allow for thermal expansion. Bottles should be stored in a controlled temperature environment.

Is NMP soluble in water?

N-Methyl-2-Pyrrolidone (NMP) is a high boiling, polar aprotic, low viscosity liquid. NMP has a good solvency for a wide range of organic and inorganic compounds and it is miscible with water at all temperatures and has a high chemical and thermal stability.

Does NMP evaporate?

First, NMP is a very slow evaporating solvent. It has a boiling point of 202°C. A thin film of NMP requires over 15,000 s for 90% evaporation at room temperature. The most effective fast-evaporating solvent for these resins is DMF, but that solvent has serious safety issues.

Is NMP a VOC?

NMP is considered a volatile organic compound (VOC) and is a California Prop 65 substance.

What is the application of 1-methyl-2-pyrrolidinone?

Application 1-Methyl-2-pyrrolidinone may be used as a solvent in the following processes: Preparation of 2-aryl and 2-alkyl benzothiazoles. Ullmann coupling reaction of aryl halides and phenols to form Ullmann ethers in the presence of 2,2,6,6-tetramethylheptane-3,5-dione.

How is NMP /N-methyl-2-pyrrolidone made?

Large-scale production of NMP /N-methyl-2-pyrrolidone/ is predominantly carried out by reacting gamma-butyrolactone with an excess of pure or aqueous methylamine in a high-pressure tube reactor (6-12 MPa). The reaction is exothermic and often run under adiabatic conditions with reactor temperatures in the range of 250-400 °C.

How common is 1-methyl-2-pyrrolidinone in US industrial effluent?

1-Methyl-2-pyrrolidinone was detected in 1 of 46 US industrial effluent samples (1). 1-Methyl-2-pyrrolidone is present in shale oil retort water (2,3). 1-Methyl-2-pyrrolidinone was found in shale retort water at a concentration of 3 mg/L (2).

Is 1-methyl-2-pyrrolidinone present in shale oil retort water?

1-Methyl-2-pyrrolidinone was detected in 1 of 46 US industrial effluent samples(1). 1-Methyl-2-pyrrolidone is present in shale oil retort water (2,3). 1-Methyl-2-pyrrolidinone was found in shale retort water at a concentration of 3 mg/L(2). Retort Water Treatment Cell analysis showed an influent concentration of 2.8…