What does a beta-2-transferrin test for?

What does a beta-2-transferrin test for?

In summary, the beta-2-transferrin assay is a highly sensitive and specific test for the presence of CSF in body fluids. This test has been employed successfully by otolaryngologists in the diagnosis of skull-base CSF leaks.

Where is beta-2-transferrin found?

cerebrospinal fluid
Beta-2-transferrin is a protein produced by neuraminidase activity in the brain which is uniquely found in the cerebrospinal fluid (CSF) and perilymph. Its absence in other body secretions makes its detection invaluable in diagnosing a CSF leak.

Is a beta-2-transferrin test accurate?

Conclusions The β2-transferrin assay is a reliable method for confirming suspected CSF and should be used as a primary screening method in all patients with suspected CSF leakage.

How do you test for CSF rhinorrhea?

Diagnosing a CSF leak includes an analysis of the nasal fluid for a protein called beta-2 transferrin which is most only found in cerebrospinal fluid. CT and MRI scans may also be require to determine the location and severity of the leakage.

What is Beta 2 microglobulin blood test?

What is a beta-2 microglobulin tumor marker test? This test measures the amount of a protein called beta-2 microglobulin (B2M) in the blood, urine, or cerebrospinal fluid (CSF). B2M is a type of tumor marker. Tumor markers are substances made by cancer cells or by normal cells in response to cancer in the body.

How do I get beta 2 transferrin?

If direct collection is not feasible, specimens may be collected using cotton swabs.

  1. Place cotton swab in as small a container as possible (for example: a tightly-stoppered test tube).
  2. Do NOT add any additional fluid to swab including, but not limited to, saline or microcollection fluids.
  3. Tightly seal container.

What does it mean when your beta 2 globulin is high?

High levels of B2M in cerebrospinal fluid can mean that cancer has spread to the brain and/or spinal cord.