What is a allopurinol used for?
What is a allopurinol used for?
Allopurinol is used to prevent or lower high uric acid levels in the blood. It is also used to prevent or lower excess uric acid levels caused by cancer medicines or in patients with kidney stones. A high uric acid level can cause gout or gouty arthritis (joint pain and inflammation).
What does allopurinol do to your kidneys?
Conclusions: Allopurinol decreases C-reactive protein and slows down the progression of renal disease in patients with chronic kidney disease. In addition, allopurinol reduces cardiovascular and hospitalization risk in these subjects.
When is the best time to take allopurinol?
How is it taken? Allopurinol is taken as a tablet once a day. It is usually better to take it just after eating and the tablet should be swallowed with water. It is important to drink plenty of water during the day because this will help you get rid of more urate through your kidneys.
What foods to avoid while taking allopurinol?
You should avoid purine-rich foods, such as anchovies, liver, kidneys and sardines. They can aggravate gout. You may need to avoid alcohol while taking allopurinol. Alcohol, especially beer and wine, can decrease the effectiveness of allopurinol.
Is allopurinol good for the heart?
Allopurinol reduces uric acid levels, prevents acute gout, and acts as an antioxidant, which could be beneficial among HF patients. In animal models of HF, allopurinol has been shown to improve cardiac function,12-15 reduce left ventricular dimensions,16-18 and reduce mortality.
Does allopurinol lower uric acid?
Can allopurinol raise blood pressure?
Allopurinol is associated with a small but significant reduction in BP. This effect can be potentially exploited to aid in controlling BP in hypertensive patients with hyperuricemia.
Is Egg good for uric acid?
Eggs are a good protein source for people with gout, because eggs are naturally low in purines.
What is allopurinol used to treat?
Allopurinol is used in the following conditions: Allopurinol reduces the production of uric acid. If uric acid is present in the body in excessive levels it can produce gout and kidney disease. Certain drugs given in chemotherapy can also increase uric acid levels.
When was allopurinol first approved by the FDA?
Allopurinol has been marketed in the United States since August 19, 1966, when it was first approved by FDA under the trade name Zyloprim. Allopurinol was marketed at the time by Burroughs-Wellcome.
Is it safe to take allopurinol during a gout attack?
Allopurinol. While not recommended historically, starting allopurinol during an attack of gout appears to be safe. In those already on the medication, it should be continued even during an acute gout attack. While use during pregnancy does not appear to result in harm, this use has not been well studied.
How long does it take for allopurinol to be metabolized?
Allopurinol is almost completely metabolized to oxipurinol within two hours of oral administration, whereas oxipurinol is slowly excreted by the kidneys over 18–30 hours. For this reason, oxipurinol is believed responsible for the majority of allopurinol’s effect.