What is racecadotril used for?

What is racecadotril used for?

Racecadotril (acetorphan) is an oral enkephalinase inhibitor for use in the treatment of acute diarrhoea. By preventing the degradation of endogenous enkephalins, racecadotril reduces hypersecretion of water and electrolytes into the intestinal lumen.

Which is better loperamide or racecadotril?

Results: Diarrhoea resolved rapidly with both racecadotril and loperamide (55.0 h in both groups), 92% of patients on racecadotril and 93% on loperamide being treatment successes. Racecadotril produced a significantly greater reduction in abdominal pain and distension than loperamide (P = 0.024 and 0.03, respectively).

Does racecadotril cause constipation?

AIM: Racecadotril is a specific enkephalinase inhibitor that exhibits intestinal antisecretory activity without affecting intestinal transit. Loperamide is an effective anti-diarrheal agent, but it usually induces constipation.

Is racecadotril an antibiotic?

Racecadotril, also known as acetorphan, is an antidiarrheal medication which acts as a peripheral enkephalinase inhibitor.

Is Racecadotril safe for babies?

The evidence synthesised suggests that the addition of racecadotril to ORS can reduce the length of symptoms as well as the number and volume of stools passed during the illness. The use of racecadotril appears self and well tolerated in children with acute diarrhoea.

How many Racecadotril should I take?

One capsule initially regardless of the time of day. Then, one capsule three times daily preferably before the main meals. Treatment should be continued until two normal stools are recorded. Treatment should not exceed 7 days.

How long does Racecadotril stay in your system?

Racecadotril is administered by the oral route, is well absorbed from the intestinal tract and is rapidly converted to its active metabolite thiorphan. Peak plasma levels are attained in about an hour and half life of the drug is three hours.

Is racecadotril safe for breastfeeding?

However, since no specific clinical studies are available, racecadotril should not be administered to pregnant women. Lactation: Due to the lack of information regarding racecadotril excretion in human milk, this medicinal product should not be administered to breastfeeding women.

What is the best medicine to stop diarrhea?

Two types of meds relieve diarrhea in different ways:

  • Loperamide (Imodium) slows the movement of food through your intestines, which lets your body absorb more liquid.
  • Bismuth subsalicylate (Kaopectate, Pepto-Bismol) balances out how fluid moves through your digestive tract.